Chinese skullcap (Scutellaria baicalensis), also known as Baikal skullcap is a 2007;56(6):280-283. Jeong, K., Shin, Y. C., Park, S., Park, J. S., Kim, N., Um, J. Y., Go, H., Sun, S., Lee, S., Park, W., Choi, Y., Song, Y., Kim, G., Jeon, C., Park, J., Lee, K., Bang, O., and Ko, S. G. Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice. Integr.Cancer Ther. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. J Biomed.Sci 2011;18:14. 2010;17(10):760-770. Dry extract of Scutellaria baicalensis as a hemostimulant in antineoplastic chemotherapy in patients with lung cancer. The flavones of particular interest are Baicalin and Baicalein. Zhang S, Cheng Z, Huang B, and Li J. Broncel, M. [Antiatherosclerotic properties of flavones from the roots of Scutellaria baicalensis Georgi]. Mol Carcinog. Ha, K. T., Kim, J. K., Kang, S. K., Kim, D. W., Lee, Y. C., Kim, H. M., and Kim, C. H. Inhibitory effect of Sihoga-Yonggol-Moryo-Tang on matrix metalloproteinase-2 and -9 activities and invasiveness potential of hepatocellular carcinoma. Skullcap Baicalensis, a herb used in Chinese healing, has been used for over 200 years as a relaxant, to fight anxiety, and convulsions. View abstract. It is a house of multiple medicinal compounds, especially flavonoids which have diverse anti-oxidant and anti-inflammatory properties. Anesth Analg 2003;97:1724-9. The herb also is found throughout the United States and southern Canada. Research Breakdown on Scutellaria baicalensis, https://examine.com/supplements/scutellaria-baicalensis/. 2011;39(1):217-224. Lin, X. C., Liu, X. G., Chen, X. W., Chen, W. Z., and Liang, N. C. [Inhibitory effect and its kinetic analysis of baicalein on recombinant human protein kinase CK2 holoenzyme]. In a traditional way, Chinese skullcap roots are used to treat … View abstract. J Dermatol Sci 2007;46(1):31-40. Shim K.S, Kim S.N, Kim M.H, and et al. View abstract. J Agric Food Chem 1-12-2005;53(1):8-16. 2008;31(5):707-710. This could increase how much lithium is in the body and result in serious side effects. Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others. View abstract. Stop using Baikal skullcap at least 2 weeks before a scheduled surgery. View abstract. Hao, H., Aixia, Y., Dan, L., Lei, F., Nancai, Y., and Wen, S. Baicalin suppresses expression of Chlamydia protease-like activity factor in Hep-2 cells infected by Chlamydia trachomatis. J Biol Chem 9-1-2000;275(35):27466-27472. Hua Xi.Kou Qiang.Yi.Xue.Za Zhi 2006;24(2):131-134. View abstract. Mu, X., He, G., Cheng, Y., Li, X., Xu, B., and Du, G. Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro. $11.99 Supreme Nutrition Scutellaria Supreme. 11-12-2009;126(2):320-331. View abstract. View abstract. 2004;91(1):65-68. Zhong.Yao Cai. Chang, Y. L., Shen, J. J., Wung, B. S., Cheng, J. J., and Wang, D. L. Chinese herbal remedy wogonin inhibits monocyte chemotactic protein-1 gene expression in human endothelial cells. Int Immunopharmacol. 5-24-2006;105(3):346-351. [Effects of light on flavonoids accumulation and related gene expression in suspension cultures of Scutellaria baicalensis]. Zhou, J., Qu, F., Zhang, H. J., Zhuge, X. H., and Cheng, L. Z. Kaplya, O. Lee, Y., Yeo, H., Liu, S. H., Jiang, Z., Savizky, R. M., Austin, D. J., and Cheng, Y. C. Increased anti-P-glycoprotein activity of baicalein by alkylation on the A ring. Journal of Dietary Supplements 2010;7:253. View abstract. Martin, J. and Dusek, J. Flavonoid accumulation in Scutellaria baicalensis Georgii in vitro cultures upon treatment with sodium cinnamate. The effect of he jie decoction on the TCRV beta 7 of chronic hepatitis B patients. Konoshima, T., Kokumai, M., Kozuka, M., Iinuma, M., Mizuno, M., Tanaka, T., Tokuda, H., Nishino, H., and Iwashima, A. Eur J Haematol. View abstract. Z. Park, K. I., Park, H. S., Kang, S. R., Nagappan, A., Lee, D. H., Kim, J. [Effect of Radix scutellariae on the growth and form of Porphyromanus endodontics in vitro]. Successful treatment of pediatric psoriasis with Indigo naturalis composite ointment. J Ethnopharmacol. A food supplement to support your health. Planta Med 2003;69(4):300-304. Wu, J. Blood 2-15-2008;111(4):2354-2363. Benzodiazepine binding site-interactive flavones from Scutellaria baicalensis root. Zhongguo Zhong.Yao Za Zhi 2008;33(9):1064-1066. I have been interested in Chinese skullcap for the possible anti-aging benefits. Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others. Taking Baikal skullcap along with medications that also slow clotting might increase the chances of bruising and bleeding. View abstract. followed by specifically-applicable references. Huang, Y., Tsang, S. Y., Yao, X., and Chen, Z. Y. Phytother.Res 2007;21(12):1187-1192. Hu, J. Z., and Liu, Y. W. Wogonin, a bioactive flavonoid in herbal tea, inhibits inflammatory cyclooxygenase-2 gene expression in human lung epithelial cancer cells. 4-1-2011;492(2):76-79. Immunopharmacology 2000;49:295-306. View abstract. View abstract. Regulska-Ilow, B., Biernat, J., Grajeta, H., Ilow, R., and Drzewicka, M. Influence of bioflavonoids from the radix extract of Scutellaria baicalensis on the level of serum lipids, and the development of laboratory rats fed with fresh and oxidized fats. View abstract. Blach-Olszewska, Z., Jatczak, B., Rak, A., Lorenc, M., Gulanowski, B., Drobna, A., and Lamer-Zarawska, E. Production of cytokines and stimulation of resistance to viral infection in human leukocytes by Scutellaria baicalensis flavones. Krakauer, T., Li, B. Q., and Young, H. A. J Ethnopharmacol. Lee, S. W., Song, G. S., Kwon, C. H., and Kim, Y. K. Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells. 1997;52(11-12):817-823. American and Chinese skullcap are flowering plants commonly used in natural medicine to treat a variety of conditions, including insomnia, inflammation, … Pasanen MK, Fredrikson H, Neuvonen PJ, Niemi M. Different effects of SLCO1B1 polymorphism on the pharmacokinetics of atorvastatin and rosuvastatin. Hong, T., Jeong, M. L., Zahn, M., Fay, B. View abstract. Leuk.Res 2007;31(4):523-530. Toxicology 3-4-2009;257(1-2):80-85. View abstract. Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others. Armstrong, T. S. and Gilbert, M. R. Use of complementary and alternative medical therapy by patients with primary brain tumors. 2011;10(2):184-191. Maternal and Child Health Care of China 2011;26(10):1529-1531. Tarrago, T., Kichik, N., Claasen, B., Prades, R., Teixido, M., and Giralt, E. Baicalin, a prodrug able to reach the CNS, is a prolyl oligopeptidase inhibitor. Guo, H. X., Liu, D. H., Ma, Y., Liu, J. F., Wang, Y., Du, Z. Y., Wang, X., Shen, J. K., and Peng, H. L. Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet. View abstract. View abstract. But there is not enough information to know if Baikal skullcap is the cause of these side effects. Chinese skullcap (Scutellaria baicalensis) is an herb commonly used in traditional Chinese medicine. 2000;23(5):272-274. Altavilla D, Squadrito F, Bitto A, et al. Fitoterapia 2009;80(7):448-452. Udintsev, S. N., Razina, T. G., and Iaremenko, K. V. [The antitumor effect of Baikal skullcap]. Huang, W. M., Yan, J., and Xu, J. Lin, A. M., Ping, Y. H., Chang, G. F., Wang, J. Y., Chiu, J. H., Kuo, C. D., and Chi, C. W. Neuroprotective effect of oral S/B remedy (Scutellaria baicalensis Georgi and Bupleurum scorzonerifolfium Willd) on iron-induced neurodegeneration in the nigrostriatal dopaminergic system of rat brain. Vitamin D Deficiency: How Much Vitamin D Is Enough? The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Tseng-Crank J, Sung S, Jia Q, and et al. Vopr.Onkol. Liao, H. L. and Hu, M. K. Synthesis and anticancer activities of 5,6,7-trimethylbaicalein derivatives. Skullcap is used for trouble sleeping (insomnia), anxiety, stroke, and paralysis caused by stroke. 1-19-2007;109(2):325-330. Ann Intern Med 2012;156:894-5. Song, S. H. and Wang, Z. View abstract. Che, Q. M., Huang, X. L., Li, Y. M., Kun, Z., Teruaki, A., and Masao, H. [Studies on metabolites of baicalin in human urine]. J Med Food 2009;12:1143-8. Kim, D. S., Son, E. J., Kim, M., Heo, Y. M., Nam, J. Uses for Skullcap. View abstract. Vaccine 1-8-2010;28(3):737-743. Bacteriostatic activity of combined application of Galla chinensis, Scutellaria baicalensis and Rhizoma coptidis against MRSA in vitro. Involvement of p53 in oroxylin A-induced apoptosis in cancer cells. Z., Yang, L. H., Guan, Y., and Shi, J. S. [Analysis of the 4th generation Scutellaria baicalensis Georgi with space mutagenesis via FTIR spectroscopy]. These antioxidants appear to downregulate the effects of oxidative stress on various tissues in the body including the liver. Acta Pharmacol Sin. Xu, X. F., Cai, B. L., Guan, S. M., Li, Y., Wu, J. View abstract. View abstract. View abstract. J Cell Biochem 10-1-2010;111(2):274-283. Vopr.Onkol. Chinese journal of modern developments in traditional medicine 1990;10(5):278-9. Altern.Ther.Health Med. Kimura, Y. and Sumiyoshi, M. Effects of baicalein and wogonin isolated from Scutellaria baicalensis roots on skin damage in acute UVB-irradiated hairless mice. Yin, F., Liu, J., Ji, X., Wang, Y., Zidichouski, J., and Zhang, J. Baicalin prevents the production of hydrogen peroxide and oxidative stress induced by Abeta aggregation in SH-SY5Y cells. However Baikal skullcap is not as strong as estrogen pills. The dose of your diabetes medication might need to be changed. Chinese Skullcap. 2009;110(4):1276-1287. Levy RM, Saikovsky R, Shmidt E, et al. Phytomedicine. Superfoodly September 17, 2018. Review: 4 Best Tasting Monk Fruit Sweeteners . Advertisement. Bleeding disorders. 2009;86(2):79-84. There has been research at a number of U.S, medical institutions. Food Chem Toxicol. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. View abstract. Yoo, H. H., Park, J. H., and Kwon, S. W. In vitro cytotoxic activity of some Korean medicinal plants on human cancer cell lines: enhancement in cytotoxicity by heat processing. 2007;60(5-6):294-297. Br J Pharmacol 2009;157:1410-18. J Ethnopharmacol. Baikal skullcap might slow blood clotting. View abstract. Metformin (Glucophage) is used to help decrease blood sugar. View abstract. Taking Baikal skullcap might decrease how well the body gets rid of lithium. View abstract. View abstract. Lee BH, Lee SJ, Kang TH, et al. Wang R.T, Zhang J.X, and Dong Y.J. Morgan SL, Baggott JE, Morel, L, Desmond R, and Kendrach AC. Low blood pressure: Baikal skullcap might lower blood pressure. Some medications are moved by pumps into cells. RRP: £14.99; You Save: £7.69 (51%) + 15% OFF using code: SWANSON15 at checkout (Offer ending soon) From this mysterious and even a little dangerous sounding herb comes a surprising resource for protecting our … 11-15-2009;171(1-3):508-513. Natural Product Sciences 2008;14(3):182-186. Tong, R., Mehendale, S. R., Wang, C. Z., Shao, Z., and Yuan, C. S. Comparison of antioxidant effects of various Scutellaria baicalensis fractions and the potential role of catalase upregulation. It’s a slender plant with many branches reaching two to four feet in height. 1987;33(2):80-84. There have been reports of fever and lung inflammation in people who took Baikal skullcap. Pharmacist's Letter/Prescriber's Letter. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. 105 unique references to scientific papers. Monitor your blood sugar closely. View abstract. View abstract. There is concern that it might cause extra bleeding during and after surgery. Diabetic Control. The Cherokee used skullcap to stimulate menstruation, relieve breast pain, and to encourage the expulsion of the placenta after childbirth. Mol Pharmacol 2001;60(3):507-513. Planta Med 1995;61(2):150-153. In Vivo 2004;18(4):497-503. 1-8-2007;245(1-2):269-274. View abstract. Ye, F., Wu, J., Dunn, T., Yi, J., Tong, X., and Zhang, D. Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. Smol'ianinov ES, Gol'dberg VE, Matiash MG, et al. Magnesium Threonate Benefits For Brain Too Good To Be True? Some of these medications that are changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin (Coumadin), and many others. In theory, Baikal skullcap might increase the risk of bruising and bleeding in people with bleeding disorders. Herbal teas R. 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