It is not a glucosid, and seems to be physiologically inert. An herbal supplement containing S. baicalensis reduced symptoms of osteoarthritis (22). Scutellaria Baicalensis ( Baical Skullcap ) is a plant. Researchers have known for some time that one of the top Baicalin benefits is its ability to produce neuroprotective effects. Scutellaria baicalensis is commonly known as Baikal skullcap or Chinese skullcap, which is a perennial herb belonging to the family Lamiaceae. A number of animal studies have shown improvements in focus and memory-orientated tasks after using a Baicalin extract. Baicalin benefits are great for people of all ages. Macrophages are immune cells that are involved in your body’s inflammation response. Scutellaria baicalensis extract is widely used in anti-allergic and anti-inflammatory cosmetics. Scutellaria baicalensis has antibacterial, anti-oxidant, anti-inflammatory and other effects. – anxiety and stress (Scullcap blocks overproduction of stress hormone, which is also helpful for managing headaches). Most often, it is found on the open, sunny grasslands in the higher elevations. It is perennial. However, the majority of the data today is still taken from animal studies. Roots are harvested in spring or autumn and dried. Huang Qin also known as Radix Scutellariae is the root of Scutellaria baicalensis. 2002;213:1-47. Baicalin is believed to interfere with hormonal reactions and release of histamines and bile in the body; it stimulates gallbladder activity, inhibits inflammation, as well as suppresses the activity of leukaemia-derived T-cells and replication of viruses and bacteria. Skullcap is increasingly included in skin care products for the benefits offered by its potent antioxidant, anti-inflammatory, and skin-brightening properties. These statements have not been evaluated by the Food and Drug Administration. [17] Q Wang et al., “Zinc coupling potentiates anti-HIV-1 activity of baicalin”, Biochem Biophys Res Commun. [13] VY Waisundara et al., “Scutellaria baicalensis enhances the anti-diabetic activity of metformin in streptozotocin-induced diabetic Wistar rats”, Am J Chin Med. All the scientists agree that flavonoids are the main chemicals, which display beneficial effects in the human body. It appears to be a good source for flavonoid compounds, and some components are quite potent. [1] “Scutellaria baicalensis”, Examine.com, accessed April 27, 2017. The root is used to make medicine. [12] Y Xi et al., “Baicalin Attenuates High Fat Diet-Induced Obesity and Liver Dysfunction: Dose-Response and Potential Role of CaMKKβ/AMPK/ACC Pathway”, Cell Physiol Biochem. – high cholesterol (the stimulation of the gallbladder to produce more bile results in “washing” cholesterol off the liver into the intestines and out of the body). Home » Neutraceuticals » Baicalin » Top 7 Baicalin Benefits – Chinese Skullcap, Huang Qin, Scutellaria Baicalensis, Hooded Willow Herb. The genus of Scutellaria includes approximately 300 species. Scutellaria barbata is a perennial herb that is used along with other botanicals in traditional Chinese medicine to treat bacterial infections, hepatitis, and tumors. 2000 Sep;49(3):295-306. It grows well on sandy or rocky dry soils. – influenza, pneumonia, and ear infections (the process of replication and multiplying of the viruses, bacteria, and fungi is blocked by Scutellaria; it is most effective against Candida, Streptococcus group, Staphylococcus, and others). [1], Studies have suggested that Biacalin has the potential for strong stress relief and relaxation benefits. The Scutellaria genus (Lamiaceae) contains 350 species (known as "skullcaps"). 2013 Dec;36(6):1584-91. Helps Promote Good Blood Glucose Levels, Conclusion – Top Baicalin Benefits Explored. Scutellaria baicalensis, Huang Qin, or Chinese Skullcap, is a flowering herb in the mint family that has been used for thousands of years in Traditional Chinese Medicine. It also supports liver function and benefits a healthy immune system. Further Baicalin benefits include promoting a healthy circulatory system, promoting a healthy blood sugar level, reducing inflammation, and possibly acting as an antiviral/antibiotic substance. Its blue to purple flowers are characterised by the specific shape, which resembles the scull. 3. 2005 Jun;4(3):281-6. [16] BQ Li et al., “The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines”, Immunopharmacology. Scutellaria baicalensis is native to Eastern Asia. INTRODUCTION. There is a need for more studies on the effects of Baicalin in humans. Most importantly, this has been shown during brain ischemia – a lack of blood/oxygen supply in the brain. Common substitutions for Baikal skullcap in Chinese medicine include related plants whose scientific names are Scutellaria viscidula, Scutellaria amonea, and Scutellaria ikoninikovii. ), allergies, pre-existing diseases, and current health conditions (e.g. The co… [10], Other studies have indicated that Baicalin supplements could have the potential to help reduce the fat content in your blood. [14] N Fujiwara, K Kobayashi,  “Macrophages in inflammation”, Curr Drug Targets Inflamm Allergy. [16]. [2] M Watanabe et al., “GABA and GABA receptors in the central nervous system and other organs”, Int Rev Cytol. There are different varieties. Baicalin has a long history of use in traditional Chinese medicine. Macrophages are specifically involved in the initiation, maintenance, and resolution of inflammation. [15] GW Fan et al., “Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways”, Inflammation. A medicinal extract of Scutellaria baicalensis and Acacia catechu acts as a dual inhibitor of cyclooxygenase and 5-lipoxygenase to reduce inflammation. Baicalin is a great herbal supplement for health benefits. This information is not intended to diagnose, treat, cure, or prevent any disease. The root is used as medicine and has been found to be very rich in flavinoids including baicalein, baicalin, wogonin, norwogonin, Before using Scutellaria Baicalensis, inform your doctor about your current list of medications, over the counter products (e.g. [6] HR Song et al., “Scutellaria flavonoid supplementation reverses ageing-related cognitive impairment and neuronal changes in aged rats”, Brain Inj. Studies have found that taking Baicalin before sleep enhances both the slow-wave sleep (SWS) and REM sleep phases. – allergies and asthma (herb’s baicalin controls hormonal reactions and histamine release upon exposure to allergy triggers). A preliminary study of S. baicalensis along with metformin appeared to improved glucose tolerance, inflammation, and gut microbiota in patients with type 2 diabetes (23). [11] HX Guo et al., “Long-term baicalin administration ameliorates metabolic disorders and hepatic steatosis in rats given a high-fat diet”, Acta Pharmacol Sin. American Skullcap. Plamed develops Scutellaria baicalensis root … Baikal skullcap is used to treat respiratory infections, hay fever, and fever. Health Benefits Memory Impairment. Scutellaria: 17 properties, uses and benefits The scutellaria belonging to the Labiatae family, is a plant used in phytotherapy for its sedative, protective heart, anti-inflammatory and anti-allergic properties. Hopefully, soon scientific research will provide more information on the hidden power of the herb, its benefits, and what is even more important, on its practical use, dosage, and risks. [5]  J Dai et al., “Activations of GABAergic signaling, HSP70 and MAPK cascades are involved in baicalin’s neuroprotection against gerbil global ischemia/reperfusion injury”, Brain Res Bull. Furthermore, the animals that were given Baicalin had significantly lower cholesterol, free fatty acid, and insulin levels in their blood. It is a relatively practical and common Chinese herbal medicine with a medicinal history of over 2000 years. In traditional Chinese medicine it is call Huang Qin. Best used for Liver Problems. Two petals of the flower are often called lips. Heals Allergic conditions. It appears to be a good source for flavonoid compounds, and some components are quite potent. [10] M Hermann et al., “Nitric oxide in hypertension”, J Clin Hypertens (Greenwich). For example, an animal study from 2001 found that Baicalin was as effective as Piracetam in enhancing focused attention. [3], Furthermore, although Baicalin is not known for producing sedative effects, researchers have found that it may enhance your sleeping patterns. There is also still a need for further research into the effects of Biacalin extract on learning in human participants as most studies have been conducted in animals. [8], One important way that Baicalin extracts help to promote a healthy circulatory system is by enhancing nitric oxide levels in your blood. [6], Researchers have even shown that Baicalin extracts may be as effective as some Nootropic substances in promoting enhanced memory and learning. 1. Huang Qin Alcohol-FREE Liquid Extract, Huang Qin, Scutellaria (Scutellaria Baicalensis) Root Glycerite Herbal Supplement 2 oz 4.5 out of 5 stars 46 $24.95 [4]. Skullcap is also known as Chinese Skullcap and Baikal Skullcap. Hopefully, soon scientific research will provide more information on the hidden power of the herb, its benefits, and what is even more important, on its practical use, dosage, and risks. Scutellaria baicalensis is also called Baical or Chinese Scutellaria, or Scullcap. Chinese skullcap (Scutellaria baicalensis), also known as Baikal skullcap is a It is due to its influence plant’s root is a so valuable herbal remedy against many diseases. – diabetes and atherosclerosis (bacterial infection, often linked to the development of atherosclerosis, in reduced by Scutellaria, as well as swelling of the arteries linings due to injuries). American skullcap (Scutellaria lateriflora) is a perennial herb native to North America. Baicalin is calming. May Help to Boost Learning Capacity, 4. 2013;77(3):657-9. It grows abundantly in the regions of Lake Baical, eastern Siberia, and northern China. This is especially relevant to macrophages and immune cells. Today, Baicalin extracts are used as a powerful dietary supplement. Compounds found in skullcap may help slow the growth of prostate cancer tumors, suggests a 2005 study... Benign Prostatic Hyperplasia. Scutellaria baicalensis, also known as Baikal skullcap or huang qin, is frequently used in homeopathic medicine. Research has recommended that the compounds found in skullcap may help slow the growth of... 2. Scutellaria baicalensis protects vascular endothelia and prevents thrombotic tendencies by inhibiting TXA 2 release to inhibit arterial vasoconstriction, preventing platelet aggregation [151,158], decreasing expression of ELAM-1 and ICAM-1 [84,159], reducing [Ca 2+] elevation, and preventing the decrease of t … [3] F Wang et al., “GABA A receptor subtype selectivity underlying selective anxiolytic effect of baicalin”, Neuropharmacology. 2013 Jan;90:1-9. However, maintaining healthy blood sugar levels is also important for otherwise healthy people. – hypertension (diuretic ability of Scutellaria helps lower blood pressure and dilate blood vessels). Testing on mouse, rabbit, and guinea pig skin revealed that a standardized extract of this ingredient is not irritating or sensitizing, even when the skin was compromised. [8] C Chen et al., “Baicalin attenuates Alzheimer-like pathological changes and memory deficits induced by amyloid β1–42 protein”, Metabolic Brain Disease, April 2015, Volume 30, Issue 2, pp 537–544. Scutellaria baicalensis (Chinese Skullcap) is a traditional chinese medicine for the purposes of cardiovascular and cognitive health as well as longevity. [15], Baicalin has also been shown to interrupt the activity of chemokines in inflammation. American skullcap has long been used in North America for anxiety and the promotion of relaxation. 2009 Feb;23(2):146-53. It has a wide range of health benefits including the promotion of relaxation and stress relief, neuroprotection, and boosting memory and learning potentials. Scutellaria baicalensis georgi is a popular remedy among herbalists and those people, who seek for diseases elimination with natural means. It’s a slender plant with many branches reaching two to four feet in height. Health benefits of Baikal Skullcap 1. 1. In bloom, the plant is covered in tiny, tubular blue flowers, although color can vary (2). Scutellaria: General Info and Health Benefits in Details, Guarana – Natural Stimulant from Amazon Banks. Scutellaria Baicalensis Root is a traditional Chinese medicinal herb known for benefiting Cardiovascular Health. The flowers, blooming in July, are situated on one side of the stem. – chronic fatigue syndrome (zinc found in the plant helps prevent this disease). Used alone or in combination with other herbs, Baikal skullcap is a highly potent herb that one should take in manageable dosage in … This medicinal plant references two herbs: American skullcap (Scutellaria lateriflora) and Chinese skullcap (Scutellaria baicalensis), with each being used to improve different conditions. It is almost skinless. pregnancy, upcoming surgery, etc. – heart attack (the risk of heart attack is significantly reduced due to Scullcap’s cholesterol-lowering effect). View abstract. Chemical composition of the plant includes flavonoids (scutellarin,baicalin, and wogonin), steroidal saponins, alkaloids, glycosides, volatile oils, iridoids and tannins, due to which the herb is widely used and is believed to have power to treat health disorders. Extracts, tablets, capsules, fluidextracts of Scutellaria baicalensis root chemicals can be found on sale these days. – headache and hangover (the herb prevents the inflammation of the brain cells caused by histamine release in response to high levels of alcohol in blood). [2], Baicalin is specific in that it only targets the GABAA receptors (specifically alpha2- and alpha3- subtypes). It treats diseases associated with heat as fever, Irritability, Thirst, Cough and Expectoration of thick, yellow sputum. Save my name, email, and website in this browser for the next time I comment. [7] YZ Shang et al., “Improving effects of SSF on memory deficits and pathological changes of neural and immunological systems in senescent mice”, Acta Pharmacol Sin. It has the chemical formula C 21 H 11 O 18 and a molecular mass of 446,364 g/mol. Buy Our Baicalin Supplement . Baicalin is a flavone glycoside, the glucuronide of baicalein, which is obtained through the binding of glucuronic acid to baicalein. Scientists have found that even a very low dosage of Baicalin is effective at raising nitric oxide levels. 2015;35(6):2349-59. 2008;36(3):517-40. 2004 Nov 12;324(2):605-10. The studies conducted by this time support this theory. It is primarily used in Asian countries as an herbal supplement. However, limited quality clinical trials are available to support these uses. Cosmetics are mainly made from its dried roots. Scientists suggest that Baicalin’s interaction with the GABA system, with heat shock protein 70 (HSP70), and with mitogen-activated protein kinases (MAPKs), are all mechanisms behind its extraordinary ability to provide protection to your brain. Subscribe to our  newsletter to get the best content straight in your inbox. Baicalin produces a reduction in the activity of selected chemokines. Fighting bacteria, viruses and fungi. Scutellaria baicalensis seems to be a good antiviral, antibacterial, antifungal, and anti-inflammatory agent. Baicalin is said to be the most powerful and promising flavonoid peculiar for this herb. Relaxation and Stress Release – Skullcap for Calm! There are a number of different names that people use for Baicalin. From: Bioactive Food as Dietary Interventions for Arthritis and … It is used to clear heat and dry dampness. Baicalin is a phytochemical and bioflavonoid found in the Baikal Skullcap plant and has been used in Traditional Chinese Medicine (TCM) for hundreds of years. [9] Z Chen et al., “Identification of a nitric oxide generation-stimulative principle in Scutellariae radix”, Biosci Biotechnol Biochem. Baikal Skullcap is beneficial for dealing with allergic conditions like asthma, hay fever,... 3. Description. Baicalin exhibited its antiinflammatory effects by reducing the elevated levels of proinflammatory cytokines, IL-1, IL-6, and TNF-α in the lung tissues through regulation of the p38 MAPK signaling pathway. Blood sugar levels are especially important for people suffering from diabetes. 2006 Dec;8(12 Suppl 4):17-29. These include the Chinese Skullcap, Huang Qin, Scutellaria baicalensis (the scientific name), and the Hooded Willow Herb. Scutellaria baicalensis georgi is a popular remedy among herbalists and those people, who seek for diseases elimination with natural means. For example, studies have found that Baicalin improve the functions of AMPK enzyme, which is known to reduce blood sugar levels. The herb is also reported to be wonderfully effective in stroke management and erectile dysfunction in blood disorders sufferers. Baikal skullcap has been used for anti-inflammatory, antioxidant, immunoprotective, anticancer, antimicrobial, antiviral, and circulatory conditions. Baicalin acts on the GABA receptors in your brain, which are your body’s natural relaxation receptors. The root of the herb is thick and branchy. It is also used as a diuretic, and should not be confused with Scutellaria baicalensis.. Specifically, how do the Baicalin benefits elucidated in animal models prove to work in humans? Scutellaria baicalensis (Chinese Skullcap) is a traditional chinese medicine for the purposes of cardiovascular and cognitive health as well as longevity. They are believed to possess anticancer abilities. These top Baicalin benefits are all recorded in various scientific journals by prestigious scientists. [5], Studies have indicated that Baicalin extracts may have an ability to enhance memory and learning abilities. Scutellaria Baicalensis Root Benefits & Information. The plant is widespread in temperate regions and tropical mountainous areas, in Europe, North America and East Asia. Baikal skullcap root extract epitomizes the new class of natural antioxidants that provide multiple skin benefits. [4] HH Chang et al., “Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation”, J Ethnopharmacol. It seems that the mechanism involved is a binding activity to the estrogen receptors of macrophages. J Med Food 2007;10:442-51. The reason is that the amount of beneficial herbal components is higher in the older plants. Baicalin appears to involve intestinal microflora for its metabolism into baicalein, the most active metabolite of baicalin. It has four-angled stems with multiple opposite leaves. It is a perennial herb, which grows to a height of 1-4 feet. [9], Nitric oxide is important in maintaining a health blood pressure. What is Scutellaria Baicalensis? [14], Studies have shown that extracts from the Chinese Skullcap can activate the anti-inflammatory activity of macrophages. Animal studies showed that after 16 weeks of Baicalin use, animals on a high-fat diet had a lower weight and less fat accumulated in their livers than those not on Baicalin. There are over 200 plants that are referred to as skullcap, therefore, it is important to check the botanical name, Scutellaria baicalensis, to ensure … [11]. 2. In a 2008 study on mice, scientists discovered that oroxylin A (an antioxidant found in the roots of... Prostate Cancer. This is thought to be the reason that the Baicalin benefits of relaxation and stress-relief occur without negative side effects like sedation or lethargy. In vitro studies suggest that S. barbata has antibacterial , antioxidant , antimutagenic , and anticancer properties. Most powerful and promising flavonoid peculiar for this herb skullcap or Chinese skullcap, Huang Qin, frequently... Forms of skullcap are used to clear heat and dry dampness periodontal disease ) controls hormonal reactions and release! 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